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Search Results for " s 100 "

80

抑制剂 & 化合物

12

天然产物

51

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T71918	DC-S100
	DC-S100 is a selective histone methyltransferase SET7 inhibitor.
T62536	S100P-IN-1	Others	Others
	S100P-IN-1 是一种高效的 S100P 抑制剂。S100P-IN-1 对胰腺癌 (pancreatic) 细胞具有抗转移作用。
T10252L2	ADU-S100 ammonium salt ML RR-S2 CDA ammonium salt,MIW815 ammonium salt	STING	Immunology/Inflammation
	ADU-S100 ammonium salt (ML RR-S2 CDA ammonium salt) 是干扰素基因刺激物的激活剂。 ADU-S100 ammonium salt 可导致有效的全身性肿瘤消退和免疫。
T10252L3	ADU-S100 ML RR-S2 CDA,MIW815	Others	Others
	ADU-S100 is an activator of stimulator of interferon genes (STING).
T10252	ADU-S100 disodium salt ML RR-S2 CDA disodium salt,MIW815 disodium salt	Others	Others
	ADU-S100 (MIW815) disodium salt is an activator of stimulator of interferon genes (STING).
T63373	S100A2-p53-IN-1
	S100A2-p53-IN-1（化合物 51）是一款针对S100A2-p53相互作用的抑制剂，专用于阻断S100A2与p53的相互作用。作为一种与Ca2+结合并参与细胞信号传递的蛋白，S100A2在胰腺癌中表达上调。S100A2-p53-IN-1特别针对MiaPaCa-2胰腺癌细胞系，显示出良好的生长抑制效果（GI50为1.2-3.4 μM）。
T74700	Mal-VC-PAB-(N-Me-amide-C3)-ADU-S100 triethylamine
	Mal-VC-PAB-(N-Me-amide-C3)-ADU-S100 triethylamine 是一种免疫刺激物抗体偶联物 (ISAC)，包含抗人表皮生长因子受体 2 (HER2) 抗体、STING 激动剂 (ADU- S100) 和一个连接子。Mal-VC-PAB-(N-Me-amide-C3)-ADU-S100 triethylamine 可用于癌症研究。
T10252L	ADU-S100 enantiomer ammonium salt MIW815 enantiomer ammonium salt,ML RR-S2 CDA enantiomer ammonium salt	Others	Others
	ADU-S100 (MIW815) enantiomer ammonium salt is the less active enantiomer of ADU-S100. ADU-S100 is an activator of the stimulator of interferon genes (STING).
TQ0113	Iclaprim 艾拉普林,AR-100	Antibacterial; Antibiotic	Microbiology/Virology
	Iclaprim (AR-100) 是一种细菌二氢叶酸的选择性新型抑制剂, 可抑制金黄色葡萄球菌的生长, 其 MIC90值为 0.06 μg/mL。
T35033L	(S)-Vamicamide (S)-Vamicamide (Iso-132373-81-0)	AChE	Neuroscience
	(S)-Vamicamide 是一种新型抗抗胆碱能化合物。Vamicamide 在 32 mg/kg 或更高（p.o.）时增加小鼠的自发运动活动，并在 100 mg/kg 时抑制小鼠强直性惊厥。
T5371	L-BUTHIONINE-(S,R)-SULFOXIMINE L-Butionine sulfoximine,丁硫氨酸-亚砜亚胺	Others; Ferroptosis	Apoptosis; Others
	L-Buthionine-(S,R)-sulfoximine 是一种细胞渗透性和不可逆的 γ-谷氨酰半胱氨酸合成酶抑制剂，通过消耗 GSH 诱导细胞中的氧化应激，可降低细胞内谷胱甘肽的水平，其对黑色素瘤、乳腺卵巢癌标本的 IC50值分别为1.9 μM、8.6 μM 和29 μM。
T1850	Balicatib AAE581,巴利卡替	Cysteine Protease	Proteases/Proteasome
	Balicatib (AAE581) 是组织蛋白酶K 抑制剂，其对组织蛋白酶K 的抑制作用是组织蛋白酶B、L 和S 的抑制性的10到100倍。
T4978	Sarpogrelate hydrochloride 盐酸沙格雷酯,MCI-9042	5-HT Receptor	GPCR/G Protein; Neuroscience
	Sarpogrelate hydrochloride (MCI-9042) 是一种选择性5-HT2R 拮抗剂，可用于研究与血栓形成有关的血管疾病，对 5-HT2A、5-HT2B 和 5-HT2C 受体的pKi 值分别为 8.52、6.57 和 7.43。
T36141	Boscalid	Mitochondrial Metabolism	Metabolism
	Boscalid 是一种广谱羧酰胺类杀菌剂，通过与线粒体复合物 II/琥珀酸脱氢酶的泛醌位点结合来抑制真菌呼吸。
T35610	2,5-dimethyl Celecoxib	Apoptosis; Wnt/beta-catenin; Prostaglandin Receptor	Apoptosis; Cytoskeletal Signaling; GPCR/G Protein; Immunology/Inflammation; Stem Cells
	2,5-dimethyl Celecoxib 是塞来昔布衍生物和微粒体前列腺素 E 合酶 1 (mPGES-1) 的靶向抑制剂，mPGES-1 是炎症介质 PGE2 合成途径中的关键酶。
T10587	BPH-652	Others	Others
	BPH-652 is an S. aureus dehydrosqualene synthase (CrtM) inhibitor (Ki: 1.5 nM; IC50: 100-300 nM for S. aureus pigment formation).
T41187	(S)-ZINC-3573
	(S)-ZINC 3573 is a negative control for (R)-ZINC 3573. (S)-ZINC 3573 displays no activity at MRGPRX2 at concentrations below 100 μM.
T11864	Iptacopan LNP023	Others	Others
	Iptacopan (LNP023) 是一种与factor B 亲和力较高的抑制剂。
T36351	Suc-AAP-Abu-pNA
	Suc-AAP-Abu-pNA 是胰腺弹性蛋白酶的特异性底物 (Km = 100 μM; Kcat/Km = 35,300 s-1 M-1 for rat pancreatic elastase; Km = 30 μM; Kcat/Km = 351,000 s-1 M-1 for porcine pancreatic elastase)。
T37395	13(S)-HpOTrE(γ)
	13(S)-HpOTrE(γ) is a monohydroxy PUFA produced by the action of soybean lipoxygenase-1 (LO-1) on γ-linolenic acid. Further action of soybean LO-1 converts 13(S)-HpOTrE(γ) to all four isomers of 6,13-DiHOTrE. At concentrations greater than 100 μM, 13(S)-HpOTrE(γ) inhibits the activity of soybean LO-1.
T37158	8(S)-HETE
	8(S)-HETE is a major lipoxygenase product in PMA-treated murine epidermis. It activates mouse keratinocyte protein kinase C with an IC50 of 100 μM. 8(S)-HETE also activates PPARα selectively at concentrations as low as 0.3 μM. Stereochemical assignment of the (S) enantiomer is based on comparison of chiral HPLC retention times to published results.
T35759	Cardol triene
	Cardol triene is a phenol found in cashew nut shell liquid that competitively and irreversibly inhibits mushroom tyrosinase (IC50 = 22.5 μM). It is schistosomicidal, killing 25, 75, and 100% of S. mansoni worms after 24 hours when used at concentrations of 50, 100, or 200 μM, respectively. It has been used as a starting material for the synthesis of bis-benzoxazines.
T73115	(S)-HH2853
	(S)-HH2853 是一种 PYRIDINO 五元芳环化合物，一种有效的 EZH1/2双重抑制剂，对 EZH2_Y641F 的IC50为 <100 nM。(S)-HH2853有潜力用于抗肿瘤或自身免疫性疾病的研究。
T60410	ART-IN-1
	ART-IN-1 (compound 7) 是一种 PARP 的选择性抑制剂，对 PARP2, TNKS2, PARP10, PARP14, PARP15 的 IC50值分别为 19, 22, 2.4, >100, 1.1 μM。
T37486	1-Stearoyl-2-15(S)-HpETE-sn-glycero-3-PC
	1-Stearoyl-2-15(S)-HpETE-sn-glycero-3-PC is a phospholipid that contains stearic acid at the sn-1 position and 15(S)-HpETE at the sn-2 position. It is produced via oxidation of 1-stearoyl-2-arachidonoyl-sn-glycero-3-PC by 15-lipoxygenase (15-LO). 1-Stearoyl-2-15(S)-HpETE-sn-glycero-3-PC is toxic to human umbilical vein endothelial cells (HUVECs) when used at a concentration of 100 μM.
T35487	Anacardic Acid Diene
	Anacardic acid diene is a polyunsaturated form of anacardic acid that has been found in cashew nut shell liquid. It has antibacterial activity against methicillin resistant S. aureus (MRSA) and S. mutans (MICs = 12.5 and 6.25 μg/ml, respectively). Anacardic acid diene has schistosomicidal activity against adult S. mansoni worms when used at a concentration of 100 μM. It also inhibits soybean lipoxygenase-1 in a time-dependent manner.
T63402	(S,R)-WT IDH1 Inhibitor 2
	(S,R)-WT IDH1 Inhibitor 2 是选择性的、有效的突变型 IDH1抑制剂，能够抑制 R132G (IC50: 2.9 nM)、R132C (IC50: 3.8 nM)、R132H (IC50: 4.6 nM) 和 WT IDH1 (IC50: 46 nM)，选择性比 IDH2 高出 100 倍。(S,R)-WT IDH1 Inhibitor 2 具有诱导细胞内 2-HG 减少，髓细胞分化阻滞失效的作用，并且在白血病母细胞和更不成熟的干细胞水平诱导粒细胞分化，可研究用于急性髓系白血病 (AML) 及其他癌症。
T36397	TAN 420E
	TAN 420E is a bacterial metabolite originally isolated from Streptomyces. It scavenges 2,2-diphenyl-1-picrylhydrazyl radicals in a cell-free assay (IC50 = 1.3 μM) and reduces thiobarbituric acid reactive substances (TBARS) in rat liver microsomes by 72% when used at a concentration of 100 μg/ml. TAN 420E is active against B. brevis, B. cereus, M. flavus, and S. aureus (MICs = 50-100 μg/ml). It is cytotoxic to P388 and KB lymphocytic leukemia cells (EC50s = 0.022 and 0.3 μg/ml, respectively).
T37460	Lipoxin B4 Lipoxin B4
	Lipoxin B4 (LXB4) is a positional isomer of LXA4 produced by the metabolism of 15-HETE or 15(S)-HpETE by human leukocytes. At a concentration of 100 nM, LXB4 inhibits polymorphonuclear leukocyte (PMN) migration stimulated by leukotriene B4 and inhibits LTB4-induced adhesion of PMNs with an IC50 value of 0.3 nM.
T35467	(±)18-HETE
	(±)18-HETE is the racemic version of a cytochrome P450 (CYP450) metabolite of arachidonic acid. When formed by the CYP2E1 isoform, 18-HETE is comprised 100% of the (R) isomer. 18(R)-HETE dose-dependently stimulates vasodilation of the rabbit kidney, whereas 18(S)-HETE does not affect perfusion pressure. 18-HETE has negligible effects on ATPase activity. 18(R)-HETE at 1 μM completely blocks 20-HETE-induced vasoconstriction of renal arterioles.
T36385	Ansatrienin A
	Ansatrienin A is an ansamycin antibiotic and antifungal agent first isolated from S. collinus and S. rishiriensis. In fetal rat long bones, it is an inhibitor of parathyroid hormone-induced calcium release (IC50 = 64 nM), which is a measure of bone resorption, and pp60c-srcM kinase (IC50 = 100 nM). It also inhibits TNF-α-induced expression of intercellular adhesion molecule-1 (ICAM-1; IC50 = 570 nM). Early in vitro studies showed that ansatrienin A potentiates the chemotherapeutic action of 5-fl...
T36409	Roccellic Acid
	Roccellic acid is a lichen secondary metabolite that has been found in R. montagnei and has antibacterial and anticancer activities.1,2 It is active against the bacteria S. gordonii and P. gingivalis (MIC = 46.9 μg/ml for both).1 Roccellic acid (100 μg/ml) inhibits proliferation of MDA-MB-231, MCF-7, and DLD-1 cancer cells by 65.3, 75.8, and 87.9%, respectively.2 \|1. Sweidan, A., Chollet-Krugler, M., Sauvager, A., et al. Antibacterial activities of natural lichen compounds against Streptococcus ...
T36336	Burnettramic Acid A
	Burnettramic acid A is a fungal metabolite originally isolated fromA. burnettiithat has diverse biological activities.1It is active againstB. subtilis,S. aureus,C. albicans, andS. cerevisiae(IC50s = 2.3, 5.9, 0.5, and 0.2 μg/ml, respectively). Burnettramic acid A is cytotoxic to NS-1 murine myeloma cells but not neonatal foreskin fibroblasts (IC50s = 13.8 and >100 μg/ml, respectively). 1.Li, H., Gilchrist, C.L.M., Lacey, H.J., et al.Discovery and heterologous biosynthesis of the burnettramic aci...
T37506	MCTR2 MCTR2
	Maresin conjugates in tissue regeneration 2 (MCTR2) is a specialized pro-resolving mediator (SPM) synthesized from docosahexaenoic acid in macrophages at the site of inflammation. DHA is oxidized to maresin 1 , which is converted to MCTR1 by glutathione S-transferase Mu 4 or leukotriene C4 synthase then to MCTR2 by γ-glutamyl transferase. MCTR2 accelerates tissue regeneration in planaria (1 and 100 nM). Pretreatment with MCTR2 prior to E. coli administration reduces neutrophil infiltration, shor...
T83926	S-Geranylgeranyl-L-glutathione GGG
	S-Geranylgeranyl-L-glutathione是孤儿G蛋白偶联受体（GPCR）P2RY8的配体。该化合物在100 nM浓度下，选择性地诱导P2RY8而非鞘氨醇-1-磷酸受体2（S1P2）、GPR55、半胱氨酸白三烯受体1（CysLT1 receptor）以及CysLT2 receptor的内吞作用。在10 nM浓度下，S-Geranylgeranyl-L-glutathione抑制了表达P2RY8的WEHI-231 B细胞淋巴瘤细胞和分离的人扁桃体生发中心B细胞由趋化因子（C-X-C motif）配体12（CXCL12）诱导的迁移。
T37094	(S)-UFR2709 hydrochloride (S)-UFR2709 hydrochloride
	(S)-UFR2709 (hydrochloride) is a competitive nAChR antagonist and displays higher affinity for α4β2 nAChRs than for α7 nAChRs. (S)-UFR2709 (hydrochloride) decreases anxiety and reduces ethanol consumption and ethanol preference in alcohol-preferring rats. (S)-UFR2709 (hydrochloride) acts as an anxiolytic agent and can be used for the study of nicotine addiction[1][2]. Brain nicotinic acetylcholine receptors (nAChRs) is a heterogeneous family of pentameric acetylcholine-gated cation channels, whi...
T37844	Kigamicin C
	Kigamicins are natural antitumor antibiotics that selectively kill pancreatic cancer PANC-1 cells only under nutrient-starved conditions. They also show antimicrobial activity against Gram-positive bacteria, including methicillin-resistant S. aureus. Kigamicin C inhibits PANC-1 cell survival in nutrient-deprived media at a 100-fold lower concentration than that required for cells maintained in nutrient-rich media. A related compound, kigamicin D, is active in vivo, suppressing the tumor growth o...
T37505	MCTR1 MCTR1
	Maresin conjugates in tissue regeneration 1 (MCTR1) is a specialized pro-resolving mediator (SPM) synthesized from docosahexaenoic acid in macrophages at the site of inflammation. DHA is oxidized to maresin 1 , which is then converted to MCTR1 by glutathione S-transferase Mu 4 or leukotriene C4 synthase. MCTR1 accelerates tissue regeneration in planaria (1 and 100 nM). Pretreatment with MCTR1 (50 ng/mouse, i.p.) prior to E. coli administration reduces neutrophil infiltration, shortens the inflam...
T83661	17(R,S)-Benzo-Resolvin D1 17(R,S)-Benzo-RvD1,Benzo-RvD1
	17(R,S)-Benzo-resolvin D1 (benzo-RvD1) 是专门的分辨介质 (SPM) RvD1 的衍生物。在10和100 nM的浓度下，它能减少PDGF-BB诱导的人类血管平滑肌细胞 (VSMCs) 的细胞骨架变化，并抑制PDGF诱导的这些细胞的迁移。Benzo-RvD1 (10 nM) 抑制人脐静脉内皮细胞 (HUVECs) 中的p65核转位。它还提高了RAW 264.7对S. aureus和zymosan颗粒的吞噬作用。
T35690	Myceliothermophin E
	Myceliothermophin E is a polyketide-amino acid hybrid fungal metabolite that has been found inT. thermophilusand has anticancer and antimicrobial activities.1,2It is cytotoxic to DLD-1, Hep3B, HepG2, and HGC-27 cancer cells (IC50s = 0.32, 0.42, 0.26, and 0.08 μg/ml, respectively).1Myceliothermophin E is active against methicillin-resistant, but not -sensitive,S. aureus(MICs = 15.8 and >100 μM, respectively).2 1.Gao, Y.-L., Zhang, M.-L., Wang, X., et al.Isolation and characterization of a new cyt...
T38151	Germicidin A
	Germicidin A is a pyranone originally derived from S. viridochromogenes that acts as a reversible, autoregulative inhibitor of spore germination and hyphal elongation in the genus Streptomyces at concentrations as low as 200 pM. During germination, spores of Streptomyces excrete germicidin A along with other germicidin homologs, which inhibit germination of its own arthrospores. At higher concentrations, germicidin A can inhibit the porcine Na+/K+-activated ATPase (ID50 = 100 μM) and prevent the...
T36021	Flumequine-13C3 Flumequine-13C3
	Flumequine-13C3is intended for use as an internal standard for the quantification of flumequine by GC- or LC-MS. Flumequine is a fluoroquinolone antibiotic.1It is active againstS. aureus, S. pyogenes, B. subtilis, E. coli, P. aeruginosa, S. faecalis, andK. pneumoniae(MICs = 1-100 μg/ml). Flumequine is also active against field isolates of B. hyodysenteriae (MICs = 6.25-200 μg/ml).2It inhibits DNA gyrase, disrupting supercoiling of bacterial DNA to block transcription and replication.3In vivo, fl...
T16443	PCS1055 dihydrochloride	Others	Others
	PCS1055 dihydrochloride is an effective, selective, and competitive muscarinic M4 receptor antagonist (IC50: 18.1 nM and a Kd: 5.72 nM). PCS1055 dihydrochloride is also a potent AChE inhibitor (IC50 s: 22 nM and 120 nM for electric eel and human AChE, res
T36740	Guanosine 5’-diphosphate (sodium salt hydrate)
	Guanosine 5’-diphosphate (GDP) is a purine nucleotide and biosynthetic precursor of guanosine 5’-triphosphate .1It has been used to study the conformations of GTPases.2GDP (100 μM) activates sulfonylurea receptor 2B (SUR2B) linked to the inward-rectifier potassium channel 6.1 (Kir6.1) in HEK293T cells in a patch-clamp assay.3 1.Berg, J.M., Tymoczko, J.L., and Stryer, L.Biochemistry(2002) 2.Vetter, I.R., and Wittinghofer, A.The guanine nucleotide-binding switch in three dimensionsScience294(5545)...
T35452	β-Defensin-3 (human) (trifluoroacetate salt)
	β-Defensin-3 is a peptide with antimicrobial properties that protects the skin and mucosal membranes of the respiratory, genitourinary, and gastrointestinal tracts. It inhibits the growth of the periodontopathogenic and cariogenic bacteria F. nucleatum, S. mutans, S. sobrinus, S. salivarius, and L. casei (MICs = 12.5-100 mg/l). It also inhibits the growth of S. aureus, S. pyogenes, P. aeruginosa, E. coli, and C. albicans. β-Defensin-3 stimulates gene expression and production of IL-6, IL-10, CXC...
T37756	Phloxine B
	Phloxine B is a red dye, the USP grade of which is used as a color additive for food, drugs, and cosmetics. It has also been used as an alternative to Gram staining, to differentiate between Gram-negative and Gram-positive bacteria. At 100 μg/ml, it can inhibit methicillin-resistant S. aureus growth in vitro. Phloxine B has also been shown to modulate channel activity of wild-type cystic fibrosis transmembrane conductance regulator chloride channels (CFTR; Ki = 38 μM) and mutant delta F508 CFTR ...
T37553	(-)-Mycousnine
	(-)-Mycousnine is a microbial metabolite and derivative of usnic acid originally isolated fromM. nawaethat has antibacterial and antifungal activities.1,2It is active against the Gram-positive bacteriaB. subtilis,K. rhizophila, andS. aureus(MICs = 4, 8, and 4 g/ml, respectively) but not the Gram-negative bacteriaE. coli,S. typhimurium, andK. pneumoniae(MICs = >128 g/ml for all).2(-)-Mycousnine is also active against the fungiT. mentagrophytes,T. rubrum, andC. albicans(MICs = 25, 25, and 100 μg/m...
T37507	MCTR3 MCTR3
	Maresin conjugates in tissue regeneration 3 (MCTR3) is a specialized pro-resolving mediator (SPM) synthesized from docosahexaenoic acid in macrophages. DHA is oxidized to maresin 1 , which is converted to MCTR1 by glutathione S-transferase Mu 4 or leukotriene C4 synthase, then to MCTR2 by γ-glutamyl transferase, and to MCTR3 by dipeptidase. MCTR3 accelerates tissue regeneration in planaria (1 and 100 nM) approximately as potently as MCTR2 and more potently than MCTR1. Pretreatment with MCTR3 pri...
T36802	Bisubstrate Inhibitor 78
	Bisubstrate inhibitor 78 is an inhibitor of nicotinamide N-methyltransferase (NNMT; IC50= 1.41 μM).1It binds the NNMT active site in the binding pockets for the NNMT substrates S-adenosyl-L-methionine (SAM) and nicotinamide . Bisubstrate inhibitor 78 is selective for NNMT over histone-lysine N-methytransferase NSD2 and protein arginine methyltransferase 1 (PRMT1; IC50s = >50 μM for both). It reduces levels of 1-methylnicotinamide in, and inhibits proliferation of, HSC-2 oral cancer cells when us...
T60640	SSAO inhibitor-2
	SSAO inhibitor-2 (Compound 1) 可用于动脉粥样硬化、糖尿病及其并发症、肥胖、中风、慢性肾病、视网膜病变、慢性阻塞性肺病 (COPD)、自身免疫性疾病、多发性硬化等的研究。SSAO inhibitor-2 是氨基脲敏感性胺氧化酶 (SSAO) 抑制剂，其对人 SSAO 和 MAO-A 的IC50分别为 <10 nM 和 10-100 μM。

化合物

Cat.No: T71918

Cat.No: T62536

Target: Others

ADU-S100 ammonium salt

Cat.No: T10252L2

Synonym: ML RR-S2 CDA ammonium salt,MIW815 ammonium salt

Target: STING

Cat.No: T10252L3

Synonym: ML RR-S2 CDA,MIW815

Target: Others

ADU-S100 disodium salt

Cat.No: T10252

Synonym: ML RR-S2 CDA disodium salt,MIW815 disodium salt

Target: Others

S100A2-p53-IN-1

Cat.No: T63373

Mal-VC-PAB-(N-Me-amide-C3)-ADU-S100 triethylamine

Cat.No: T74700

ADU-S100 enantiomer ammonium salt

Cat.No: T10252L

Synonym: MIW815 enantiomer ammonium salt,ML RR-S2 CDA enantiomer ammonium salt

Target: Others

Cat.No: TQ0113

Synonym: 艾拉普林,AR-100

Target: Antibacterial, Antibiotic

Cat.No: T35033L

Synonym: (S)-Vamicamide (Iso-132373-81-0)

Target: AChE

L-BUTHIONINE-(S,R)-SULFOXIMINE

Cat.No: T5371

Synonym: L-Butionine sulfoximine,丁硫氨酸-亚砜亚胺

Target: Others, Ferroptosis

Cat.No: T1850

Synonym: AAE581,巴利卡替

Target: Cysteine Protease

Sarpogrelate hydrochloride

Cat.No: T4978

Synonym: 盐酸沙格雷酯,MCI-9042

Target: 5-HT Receptor

Cat.No: T36141

Target: Mitochondrial Metabolism

2,5-dimethyl Celecoxib

Cat.No: T35610

Target: Apoptosis, Wnt/beta-catenin, Prostaglandin Receptor

Cat.No: T10587

Target: Others

Cat.No: T41187

Cat.No: T11864

Synonym: LNP023

Target: Others

Suc-AAP-Abu-pNA

Cat.No: T36351

13(S)-HpOTrE(γ)

Cat.No: T37395

Cat.No: T37158

Cat.No: T35759

Cat.No: T73115

Cat.No: T60410

1-Stearoyl-2-15(S)-HpETE-sn-glycero-3-PC

Cat.No: T37486

Anacardic Acid Diene

Cat.No: T35487

(S,R)-WT IDH1 Inhibitor 2

Cat.No: T63402

Cat.No: T36397

Cat.No: T37460

Synonym: Lipoxin B4

Cat.No: T35467

Cat.No: T36385

Cat.No: T36409

Burnettramic Acid A

Cat.No: T36336

Cat.No: T37506

Synonym: MCTR2

S-Geranylgeranyl-L-glutathione

Cat.No: T83926

Synonym: GGG

(S)-UFR2709 hydrochloride

Cat.No: T37094

Synonym: (S)-UFR2709 hydrochloride

Cat.No: T37844

Cat.No: T37505

Synonym: MCTR1

17(R,S)-Benzo-Resolvin D1

Cat.No: T83661

Synonym: 17(R,S)-Benzo-RvD1,Benzo-RvD1

Myceliothermophin E

Cat.No: T35690

Cat.No: T38151

Flumequine-13C3

Cat.No: T36021

Synonym: Flumequine-13C3

PCS1055 dihydrochloride

Cat.No: T16443

Target: Others

Guanosine 5’-diphosphate (sodium salt hydrate)

Cat.No: T36740

β-Defensin-3 (human) (trifluoroacetate salt)

Cat.No: T35452

Cat.No: T37756

Cat.No: T37553

Cat.No: T37507

Synonym: MCTR3

Bisubstrate Inhibitor 78

Cat.No: T36802

SSAO inhibitor-2

Cat.No: T60640

Cat. No.	Product Name	Target	Signaling Pathways
T83918	Clazamycin A hydrochloride NSC 332188
	Clazamycin A是一种最初从链霉菌中分离出的抗生素和微生物代谢产物。它对多种细菌具有活性，包括S. aureus、B. anthracis、B. subtilis、E. coli和P. aeruginosa（MICs分别为100、6.25、100、50和25 µg/ml）。
TN3650	Chrysothol	Antifection	Microbiology/Virology
	Chrysothol shows strong antimicrobial activities (MICs=50-100 ug/ml) against enterobacteria E. coli and S. enteritidis. It also shows anti-cancer activity against human breast cancer cells.
TN1526	Corydalmine	P450; Antifection	Metabolism; Microbiology/Virology
	Corydalmine exhibits antibacterial activities against Staphylococcus aureus and methicillin-resistant S. aureus strains.1-Corydalmine significantly inhibits spore germination of all the fungi at 100 to 1500 ppm. l-Corydalmine also exhibits potent analgesic activity in preclinical models, it is under development as an oral analgesic agent.
TN5228	Vestitol	Antifection	Microbiology/Virology
	Vestitol is a phytoalexin with insect feeding-deterrent activity, it has antioxidant, anti-inflammatory and antimicrobial activities, it can inhibit neutrophil migration at a dose of 10 mg/kg, and shows MICs ranging from 25-50 to 50-100 ug/mL and MBCs ranging from 25-50 to 50-100 ug/mL.Vestitol exerts a limited inhibitory effect on S. hermonthica germination, it can significantly inhibit seedling growth, it also contributes, at least in part, to the host's defence mechanism and acts as a chemica...
T83916	Cytogenin
	Cytogenin（一种源自S. eurocidicum的香豆素衍生物）具有多种生物活性。在每日给药25 mg/kg剂量下，能减轻Ehrlich鼠自发性腺癌模型的肿瘤重量。在体内，Cytogenin（每日30和100 mg/kg）可减少链脲佐菌素诱导的体重下降和血浆葡萄糖水平上升，以及小鼠糖尿病模型中巨噬细胞胰腺浸润。同时，在每日100 mg/kg的剂量下，能降低小鼠巨噬细胞中zymosan和LPS诱导的一氧化氮产生，及LPS诱导的Il-6水平增加。
T36417	Nargenicin Antibiotic 47444
	Nargenicin is a macrolide antibiotic that selectively inhibits the growth of S. aureus, methicilin resistant S. aureus (MRSA), and M. luteus (MICs = 0.6, 0.3, and 2.5 μg/ml, respectively) over a panel of 11 Gram-positive and Gram-negative bacteria (MICs = >80 μg/ml). [1] It dose-dependently inhibits S. aureus DnaE in the presence of DNase I-activated DNA and E. coli DnaE when used at concentrations of 0.00001-0.1 and 0.01-100 μg/mL, respectively. [2] In murine BV-2 microglial cells, nargenicin (...
TN4471	Lysicamine	IL Receptor; Antifection	Immunology/Inflammation; Microbiology/Virology
	Lysicamine shows significant antioxidant capacity in the ORAC(FL) assay and it is active against S. epidermidis and C. dubliniensis, with MIC values in the range 12.5-100 microg mL(-1). Lysicamine has antimicrobial and anti-inflammation activity, the mini
T35409	(+)-δ-Cadinene	Apoptosis; Antibacterial	Apoptosis; Microbiology/Virology
	(+)-δ-Cadinene 是一种从G. hirsutum 中发现的倍半萜，具有抗菌、杀虫、抗癌和抗增殖活性。它对肺炎双球菌的MIC 值为31.25 μg/ml，对 A. stephensi、A. aegypti 和 C. quinquefasciatust 三龄幼虫的LC50s 值分别8.23、9. 2和3。(+)-δ-Cadinene（10、50 和 100 μM）可诱导 OVCAR-3 人类卵巢癌细胞凋亡并抑制其增殖。
T83693	Magainin 2 TFA MG2
	Magainin 2是一种从非洲爪蟾（X. laevis）皮肤中分离出的阳离子肽，具有宿主防御和抗菌活性。该化合物对细菌E. coli、K. pneumoniae、S. epidermidis、S. aureus及真菌C. albicans表现出活性（MICs分别为5、10、10、50和80 µg/ml）。Magainin 2（20 µM）能降低猕猴桃花粉的萌发率和平均管长。在被单纯疱疹病毒1型（HSV-1）或2型（HSV-2）感染的Vero细胞中，它可减少病毒复制（EC50s分别为22.16和19.8 µM），同时不影响细胞活性，其50%细胞毒性浓度值（CC50）大于100 µM。
T36329	Terpendole I
	Terpendole I is a fungal metabolite that has been found in A. yamanashiensis.1 It is a weak inhibitor of acyl-coenzyme A:cholesterol acyltransferase (ACAT; IC50 = 145 μM) and is active against the bacteria B. cereus and B. subtilis (MICs = 100 μg/ml for both) but not S. aureus, P. aeruginosa, or K. pneumoniae (MICs = >200 μg/ml for all) or the fungus C. albicans (MIC = 200 μg/ml).1,2 It is cytotoxic to HeLa cells with an IC50 value of 52.6 μM.3 \|1. Tomoda, H., Tabata, N., Yang, D.-J., et al. Ter...
T36000	3-Hydroxyterphenyllin
	3-Hydroxyterphenyllin is a p-terphenyl fungal metabolite originally isolated from A. candidus that has diverse biological activities, including antioxidant, antiproliferative, antibacterial, and antiviral properties.1,2,3,4 It has a 96% scavenging effect on 2,2-diphenyl-1-picrylhydrazyl radicals when used at a concentration of 100 μg/ml.2 3-Hydroxyterphenyllin inhibits the growth of HeLa cervical, A549 lung, and HepG2 liver cancer cells (IC50s = 23, 36, and 32 μM, respectively), as well as methi...
T38330	Collinin
	Collinin is a coumarin that has been found in Z. schinifolium and has diverse biological activities.1,2,3,4 It is active against drug-susceptible and -resistant strains of M. tuberculosis (MIC50s = 3.13-6.25 μg/ml).1 Collinin inhibits LPS-induced nitric oxide (NO) production (IC50 = 5.9 μM) and reduces COX-2 protein levels in RAW 264.7 cells.2 It completely inhibits aggregation of isolated rabbit platelets induced by arachidonic acid , collagen, or platelet activating factor (PAF) when used at a...

天然产物

Clazamycin A hydrochloride

Cat.No: T83918

Synonym: NSC 332188

Cat.No: TN3650

Target: Antifection

Cat.No: TN1526

Target: P450, Antifection

Cat.No: TN5228

Target: Antifection

Cat.No: T83916

Cat.No: T36417

Synonym: Antibiotic 47444

Cat.No: TN4471

Target: IL Receptor, Antifection

(+)-δ-Cadinene

Cat.No: T35409

Target: Apoptosis, Antibacterial

Cat.No: T83693

Synonym: MG2

Cat.No: T36329

3-Hydroxyterphenyllin

Cat.No: T36000

Cat.No: T38330

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPJ-00990	S100B Protein, Mouse, Recombinant (His) S-100 protein subunit beta,S<...	Mouse	E. coli
	S100-B, is an acidic protein with a molecular weight of 21 kDa belonging to the S100 family. S100-B contains two EF-hand-type calcium-binding motifs separated by a hinge region with a hydrophobic cleft. S100-B plays an important role in neurodevelopment, differentiation, and brain construction. S100-B has neuroprotective effects, but at high concentrations S100-B is neurotoxic. Extracellular concentration of S100-B increases following brain damage, which easily penetrates into cerebrospinal flui...
TMPY-04290	S100A8 & S100A9 Heterodimer Protein, Human, Recombinant (Flag & His) S1A8,CAGA,CFAG,CAGB,MRP8 & S1A9,MRP14	Human	Baculovirus-Insect Cells
	S100A8 & S100A9 Heterodimer Protein, Human, Recombinant (Flag & His) is expressed in Baculovirus-Insect Cells with Flag and His tag. The predicted molecular weight is 12.2 kDa. Accession number: NP_002955.2&NP_002956.1
TMPK-01369	S100B Protein, Canine, Recombinant (hFc) S100 calcium-binding,S100	Canine	HEK293
	S100B, a calcium-binding protein of the EF-hand type exerts both intracellular and extracellular functions.The intracellular, and extracellular, roles of S100B are attractive therapeutic targets for the treatment of both cardiac and vascular disease.
TMPY-02531	S100B Protein, Human, Recombinant (His) S100β,S100-B,S<...	Human	E. coli
	S100B is a member of the S100 family of proteins containing two EF-hand-type calcium-binding motifs. S100B exerts both intracellular and extracellular functions. Intracellular S100B acts as a stimulator of cell proliferation and migration and an inhibitor of apoptosis and differentiation, which might have important implications during brain, cartilage and skeletal muscle development and repair, activation of astrocytes in the course of brain damage and neurodegenerative processes, and of cardiom...
TMPY-00997	S100A1 Protein, Human, Recombinant S100-α,S100A,S<...	Human	E. coli
	S100A1 is a Ca2+binding protein of the EF-hand type that belongs to the S100 protein family. S100 proteins consisting of at least 19 members exist as dimers in the cytoplasm and/or nucleus of a wide range of cells, and are involved in the regulation of a number of cellular processes such as cell-cycle progression and cell differentiation. This protein has been shown to function in the processes including stimulation of Ca2+-induced Ca2+release, inhibition of microtubule assembly, and inhibition ...
TMPY-02532	S100A1 Protein, Mouse, Recombinant (His) AI266795,S100a,S100 calc...	Mouse	E. coli
	S100A1 is a Ca2+binding protein of the EF-hand type that belongs to the S100 protein family. S100 proteins consisting of at least 19 members exist as dimers in the cytoplasm and/or nucleus of a wide range of cells, and are involved in the regulation of a number of cellular processes such as cell-cycle progression and cell differentiation. This protein has been shown to function in the processes including stimulation of Ca2+-induced Ca2+release, inhibition of microtubule assembly, and inhibition ...
TMPY-00909	S100A1 Protein, Human, Recombinant (hFc) S100 calcium binding protein A1,S...	Human	HEK293
	S100A1 is a Ca2+binding protein of the EF-hand type that belongs to the S100 protein family. S100 proteins consisting of at least 19 members exist as dimers in the cytoplasm and/or nucleus of a wide range of cells, and are involved in the regulation of a number of cellular processes such as cell-cycle progression and cell differentiation. This protein has been shown to function in the processes including stimulation of Ca2+-induced Ca2+release, inhibition of microtubule assembly, and inhibition ...
TMPY-00913	S100B Protein, Human, Recombinant (hFc) NEF,S100 calcium binding protein B,S	Human	HEK293
	S100B is a member of the S100 family of proteins containing two EF-hand-type calcium-binding motifs. S100B exerts both intracellular and extracellular functions. Intracellular S100B acts as a stimulator of cell proliferation and migration and an inhibitor of apoptosis and differentiation, which might have important implications during brain, cartilage and skeletal muscle development and repair, activation of astrocytes in the course of brain damage and neurodegenerative processes, and of cardiom...
TMPY-01357	S100A9 Protein, Human, Recombinant (His) MRP14,P14,LIAG,CFAG,CGLB,CAGB,NIF,MIF,S100...	Human	Baculovirus-Insect Cells
	S100 protein is a family of low molecular weight protein found in vertebrates characterized by two EF-hand calcium-binding motifs. There are at least 21 different S100 proteins, and the name is derived from the fact that the protein is 100% soluble in ammonium sulfate at neutral pH. Most S100 proteins are disulfide-linked homodimer, and is normally present in cells derived from the neural crest, chondrocytes, macrophages, dendritic cells, etc. S100 proteins have been implicated in a variety of i...
TMPY-01356	S100A8 Protein, Human, Recombinant (His) 60B8AG,MRP-8,MA387,NIF,L1Ag,S100 calcium b...	Human	Baculovirus-Insect Cells
	S100A8 is a member of the S100 protein family containing 2EF-hand calcium-binding motifs. S100 proteins are involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. Altered expression of S100A8 protein is associated with various diseases and cancers. S100A8 may have an immunoregulatory role by contributing to the regulation of fetal-maternal interactions. It may play a protective role and its absence may allow infiltration by maternal cells...
TMPY-02216	S100P Protein, Human, Recombinant MIG9,S100 calcium binding protein P	Human	E. coli
	Protein S100-P, also known as Protein S100-E, S100 calcium-binding protein P, S100P and S100E, is a nucleus and cytoplasm protein that belongs to the S-100 family. S100P / S100E contains twoEF-hand domains. S100P protein regulates calcium signal transduction and mediates cytoskeletal interaction, protein phosphorylation and transcriptional control. S100P / S100E overexpression can upregulate androgen receptor expression and thereby promote prostate cancer progression by increasing cell growth. S...
TMPY-02135	S100A16 Protein, Human, Recombinant S100F,DT1P1A7,S100 calci...	Human	E. coli
	S100A16 is a member of S100 protein superfamily that carries calcium-binding EF-hand motifs. S100 proteins are cell- and tissue-specific and are involved in many intra- and extracellular processes through interacting with specific target proteins. S100A16 expression was found to be astrocyte-specific. The S100A16 protein was found to accumulate within nucleoli and to translocate to the cytoplasm in response to Ca(2+) stimulation. The homodimeric structure of human S100A16 in the apo state has be...
TMPY-01330	S100A9 Protein, Human, Recombinant CAGB,MIF,60B8AG,S100 calcium binding prote...	Human	E. coli
	S100 protein is a family of low molecular weight protein found in vertebrates characterized by two EF-hand calcium-binding motifs. There are at least 21 different S100 proteins, and the name is derived from the fact that the protein is 100% soluble in ammonium sulfate at neutral pH. Most S100 proteins are disulfide-linked homodimer, and is normally present in cells derived from the neural crest, chondrocytes, macrophages, dendritic cells, etc. S100 proteins have been implicated in a variety of i...
TMPY-01094	S100A6 Protein, Mouse, Recombinant 2A9,PRA,5B10,S100 calcium binding protein ...	Mouse	E. coli
	S100 protein is a family of low molecular weight protein found in vertebrates characterized by two EF-hand calcium-binding motifs. There are at least 21 different S100 proteins, and the name is derived from the fact that the protein is 100% soluble in ammonium sulfate at neutral pH. Most S100 proteins are disulfide-linked homodimer, and is normally present in cells derived from the neural crest, chondrocytes, macrophages, dendritic cells, etc. S100 proteins have been implicated in a variety of i...
TMPJ-01189	S100A15A Protein, Mouse, Recombinant Protein S100-A15A,S100 c...	Mouse	E. coli
	Members of the S100 protein family are involved in calcium- or zinc-dependent cellular functions and regulate immune-mechanisms, cell proliferation and differentiation. Some S100 members have been established as tumor markers because they are dysregulated during carcinogenesis. Psoriasin (S100A7) and koebnerisin (S100A15) are highly homologous proteins that have been first described in psoriasis, which is characterized by disturbed epidermal maturation and chronic inflammation. Several studies s...
TMPJ-00991	S100A8 Protein, Rat, Recombinant (His) Leukocyte L1 complex light chain,Migration inhibitory factor...	Rat	E. coli
	Protein S100-A8(Mrp8) contains 2 EF-hand domains and belongs to the S-100 family. Mrp8 binds two calcium ions per molecule with an affinity similar to that of the S-100 proteins. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. It may function in the inhi...
TMPY-02821	S100A9 Protein, Mouse, Recombinant (His) Cagb,MRP14,AW546964,60B8Ag,BEE22,S100 calc...	Mouse	E. coli
	S100 protein is a family of low molecular weight protein found in vertebrates characterized by two EF-hand calcium-binding motifs. There are at least 21 different S100 proteins, and the name is derived from the fact that the protein is 100% soluble in ammonium sulfate at neutral pH. Most S100 proteins are disulfide-linked homodimer, and is normally present in cells derived from the neural crest, chondrocytes, macrophages, dendritic cells, etc. S100 proteins have been implicated in a variety of i...
TMPY-04944	S100P Protein, Human, Recombinant, Biotinylated MIG9,S100 calcium binding protein P	Human	E. coli
	Protein S100-P, also known as Protein S100-E, S100 calcium-binding protein P, S100P and S100E, is a nucleus and cytoplasm protein that belongs to the S-100 family. S100P / S100E contains twoEF-hand domains. S100P protein regulates calcium signal transduction and mediates cytoskeletal interaction, protein phosphorylation and transcriptional control. S100P / S100E overexpression can upregulate androgen receptor expression and thereby promote prostate cancer progression by increasing cell growth. S...
TMPY-03934	S100A4 Protein, Human, Recombinant (His) 42A,18A2,PEL98,CAPL,MTS1,S100 cal...	Human	E. coli
	S100A4, also known as metastasis-associated protein Mtsl, belongs to the family of small calcium-binding S100 proteins containing two EF-hand calcium-binding motifs. In humans at least 20 S100 family members that are distributed tissue specifically have been identified, and are involved in a number of cellular processes as transducers of calcium signal. S100A4 is a symmetric homodimer, and undergoes a relatively large conformational change upon the typical EF-hand binding calcium, which is neces...
TMPJ-00917	S100P Protein, Human, Recombinant (His) Protein S100-E,S100E,	Human	E. coli
	Protein S100-P (S100P) belongs to the S100 family of Calcium-Binding Proteins. S100P is 95 amino acids in length and it contains 2 EF-Hand Calcium-Binding Motifs. The EF-Hand Motif binds calcium, which likely alters molecular conformation. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells and it is involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. In addition to binding Ca, S100P also binds Zn and M...
TMPY-01346	Psoriasin/S100A7 Protein, Human, Recombinant S100 calcium binding protein A7,PS	Human	E. coli
	Protein S100-A7, also known as S100 calcium-binding protein A7, Psoriasin, S100A7, and PSOR1, is a secreted protein which belongs to theS-100 family. S100A7 was first isolated from skin involved by psoriasis, which can be induced in cultured squamous epithelial cells. S100A7 is expressed by both normal cultured and malignant keratinocytes and malignant breast epithelial cells within ductal carcinoma in situ, suggesting an association with abnormal pathways of differentiation. S100A7 plays a role...
TMPY-04080	S100A4 Protein, Mouse, Recombinant PeL98,18A2,42a,Capl,pk9a,FSp1,metastas...	Mouse	HEK293
	S100A4, also known as metastasis-associated protein Mtsl, belongs to the family of small calcium-binding S100 proteins containing two EF-hand calcium-binding motifs. In humans at least 20 S100 family members that are distributed tissue specifically have been identified, and are involved in a number of cellular processes as transducers of calcium signal. S100A4 is a symmetric homodimer, and undergoes a relatively large conformational change upon the typical EF-hand binding calcium, which is neces...
TMPY-01879	S100A14 Protein, Human, Recombinant (His) S100 calcium binding protein A14,BCMP84,	Human	E. coli
	S100 protein is a family of low molecular weight protein found in vertebrates characterized by two EF-hand calcium-binding motifs. There are at least 21 different S100 proteins, and the name is derived from the fact that the protein is 100% soluble in ammonium sulfate at neutral pH. Most S100 proteins are disulfide-linked homodimer, and is normally present in cells derived from theneural crest, chondrocytes, macrophages, dendritic cells, etc. S100 proteins have been implicated in a variety of in...
TMPY-03699	S100A13 Protein, Mouse, Recombinant (His) S100 calcium binding protein A13,S	Mouse	E. coli
	S100 protein is a family of low molecular weight protein found in vertebrates characterized by two EF-hand calcium-binding motifs. There are at least 21 different S100 proteins, and the name is derived from the fact that the protein is 100% soluble in ammonium sulfate at neutral pH. Most S100 proteins are disulfide-linked homodimer, and is normally present in cells derived from theneural crest, chondrocytes, macrophages, dendritic cells, etc. S100 proteins have been implicated in a variety of in...
TMPY-03335	S100A3 Protein, Mouse, Recombinant (His) S100E,S100 calcium bindi...	Mouse	E. coli
	Protein S100-A3, also known as Protein S-100E, S100 calcium-binding protein A3, S100A3 and S100E, is a member of the S-100 family. S100A3 / S100E contains 2 EF-hand domains. S100A3 / S100E is highly expressed in the differentiating cuticular cells within the hair follicle and organized into mature hair cuticles. High concentrations of S100A3 homotetramer might provide the millimolar level of Ca2+required for hair cuticular barrier formation. S100A3 / S100E is a unique member of the Ca2+-binding ...
TMPY-01931	S100A5 Protein, Human, Recombinant (His) S100D,S100 calcium bindi...	Human	E. coli
	S100 protein is a family of low molecular weight protein found in vertebrates characterized by two EF-hand calcium-binding motifs. There are at least 21 different S100 proteins, and the name is derived from the fact that the protein is 100% soluble in ammonium sulfate at neutral pH. Most S100 proteins are disulfide-linked homodimer, and is normally present in cells derived from the?neural crest, chondrocytes, macrophages, dendritic cells, etc. S100 proteins have been implicated in a variety of i...
TMPY-01476	S100A13 Protein, Human, Recombinant protein S100-A13,OTTHUMP00000034802,S<...	Human	E. coli
	S100 protein is a family of low molecular weight protein found in vertebrates characterized by two EF-hand calcium-binding motifs. There are at least 21 different S100 proteins, and the name is derived from the fact that the protein is 100% soluble in ammonium sulfate at neutral pH. Most S100 proteins are disulfide-linked homodimer, and is normally present in cells derived from theneural crest, chondrocytes, macrophages, dendritic cells, etc. S100 proteins have been implicated in a variety of in...
TMPY-01466	S100A12 Protein, Human, Recombinant MRP6,MRP-6,S100A12,S100 ...	Human	E. coli
	S100 protein is a family of low molecular weight protein found in vertebrates characterized by two EF-hand calcium-binding motifs. There are at least 21 different S100 proteins, and the name is derived from the fact that the protein is 100% soluble in ammonium sulfate at neutral pH. Most S100 proteins are disulfide-linked homodimer, and is normally present in cells derived from the neural crest, chondrocytes, macrophages, dendritic cells, etc. S100 proteins have been implicated in a variety of i...
TMPY-01331	S100A11 Protein, Human, Recombinant S100C,HEL-S-43,S100<...	Human	E. coli
	Protein S100-A11, also known as S100 calcium-binding protein A11, S100A11 and MLN70, is a member of theS-100 family. S100A11 is widely expressed in multiple tissues, and is located in cytoplasm, nucleus, and even cell periphery. S100A11 exists as a non-covalent homodimer with an antiparallel conformation. Ca(2+) binding to S100A11 would trigger conformational changes which would expose the hydrophobic cleft of S100A11 and facilitate its interaction with target proteins. As a dual cell growth med...
TMPY-00998	S100A2 Protein, Human, Recombinant S100L,CAN19,S100 calcium...	Human	E. coli
	The calcium-binding protein S100A2 is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 family genes are located as a cluster on chromosome 1q21, and S100 proteins consisting of at least 20 members are involved in the regulation of a number of cellular processes such as cell-cycle progression and cell differentiation. S100A2 was first detected in lung and kidney, and is mainly expressed in a subset of tissues and cells such as breast epithelia and liver. T...
TMPY-00912	S100A6 Protein, Human, Recombinant 5B10,PRA,S100 calcium binding protein A6,C...	Human	E. coli
	S100 protein is a family of low molecular weight protein found in vertebrates characterized by two EF-hand calcium-binding motifs. There are at least 21 different S100 proteins, and the name is derived from the fact that the protein is 100% soluble in ammonium sulfate at neutral pH. Most S100 proteins are disulfide-linked homodimer, and is normally present in cells derived from the neural crest, chondrocytes, macrophages, dendritic cells, etc. S100 proteins have been implicated in a variety of i...
TMPY-02463	S100A5 Protein, Mouse, Recombinant (His) S100 calcium binding protein A5,S...	Mouse	E. coli
	S100 protein is a family of low molecular weight protein found in vertebrates characterized by two EF-hand calcium-binding motifs. There are at least 21 different S100 proteins, and the name is derived from the fact that the protein is 100% soluble in ammonium sulfate at neutral pH. Most S100 proteins are disulfide-linked homodimer, and is normally present in cells derived from the?neural crest, chondrocytes, macrophages, dendritic cells, etc. S100 proteins have been implicated in a variety of i...
TMPY-01339	S100A6 Protein, Human, Recombinant (His) 2A9,PRA,CABP,CACY,S100 calcium binding pro...	Human	Baculovirus-Insect Cells
	S100 protein is a family of low molecular weight protein found in vertebrates characterized by two EF-hand calcium-binding motifs. There are at least 21 different S100 proteins, and the name is derived from the fact that the protein is 100% soluble in ammonium sulfate at neutral pH. Most S100 proteins are disulfide-linked homodimer, and is normally present in cells derived from the neural crest, chondrocytes, macrophages, dendritic cells, etc. S100 proteins have been implicated in a variety of i...
TMPY-00911	S100A4 Protein, Human, Recombinant (hFc) 18A2,PEL98,CAPL,S100 calcium binding prote...	Human	HEK293
	S100A4, also known as metastasis-associated protein Mtsl, belongs to the family of small calcium-binding S100 proteins containing two EF-hand calcium-binding motifs. In humans at least 20 S100 family members that are distributed tissue specifically have been identified, and are involved in a number of cellular processes as transducers of calcium signal. S100A4 is a symmetric homodimer, and undergoes a relatively large conformational change upon the typical EF-hand binding calcium, which is neces...
TMPY-04111	S100A4 Protein, Mouse, Recombinant (His) Capl,FSp1,pk9a,Mts1,metastas<...	Mouse	E. coli
	S100A4, also known as metastasis-associated protein Mtsl, belongs to the family of small calcium-binding S100 proteins containing two EF-hand calcium-binding motifs. In humans at least 20 S100 family members that are distributed tissue specifically have been identified, and are involved in a number of cellular processes as transducers of calcium signal. S100A4 is a symmetric homodimer, and undergoes a relatively large conformational change upon the typical EF-hand binding calcium, which is neces...
TMPK-01259	S100A9 Protein, Cynomolgus, Recombinant (His) Calgranulin-B,MRP-14,CAGB,Calprotectin L1H subunit,...	Cynomolgus	E. coli
	S100A8 and S100A9 (also known as MRP8 and MRP14, respectively) are Ca2 binding proteins belonging to the S100 family. They often exist in the form of heterodimer, while homodimer exists very little because of the stability. S100A8/A9 is constitutively expressed in neutrophils and monocytes as a Ca2 sensor, participating in cytoskeleton rearrangement and arachidonic acid metabolism.
TMPY-02497	S100A15 Protein, Mouse, Recombinant (His & MBP) S100a17l1,Gm1020,S100a15...	Mouse	E. coli
	Koebnerisin is also known as protein S100-A7A (S100A7A), S100 calcium-binding protein A7-like 1 (S100A7L1) or S100 calcium-binding protein A15 (S100A15). Human S100A7A / S100A15 is a novel member of the S100 family of EF-hand calcium-binding proteins and was recently identified in psoriasis, where it is significantly upregulated in lesional skin. S100A7 is expressed by both normal cultured and malignant keratinocytes and malignant breast epithelial cells within ductal carcinoma in situ, suggesti...
TMPY-00910	S100A2 Protein, Human, Recombinant (hFc) S100L,CAN19,S100 calcium...	Human	HEK293
	The calcium-binding protein S100A2 is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 family genes are located as a cluster on chromosome 1q21, and S100 proteins consisting of at least 20 members are involved in the regulation of a number of cellular processes such as cell-cycle progression and cell differentiation. S100A2 was first detected in lung and kidney, and is mainly expressed in a subset of tissues and cells such as breast epithelia and liver. T...
TMPH-01951	S100A7A Protein, Human, Recombinant (His)	Human	Yeast
	S100A7A Protein, Human, Recombinant (His) is expressed in Yeast.
TMPH-03357	S100A4 Protein, Rat, Recombinant (His & Myc)	Rat	E. coli
	S100A4 Protein, Rat, Recombinant (His & Myc) is expressed in E. coli.
TMPY-03938	S100A4 Protein, Mouse, Recombinant (hFc) metastasin,pk9a,18A2,FSp1,42a,PeL...	Mouse	HEK293
	S100A4, also known as metastasis-associated protein Mtsl, belongs to the family of small calcium-binding S100 proteins containing two EF-hand calcium-binding motifs. In humans at least 20 S100 family members that are distributed tissue specifically have been identified, and are involved in a number of cellular processes as transducers of calcium signal. S100A4 is a symmetric homodimer, and undergoes a relatively large conformational change upon the typical EF-hand binding calcium, which is neces...
TMPY-03700	S100A11 Protein, Mouse, Recombinant (His) Emap1,S100a14,S100 calci...	Mouse	E. coli
	Protein S100-A11, also known as S100 calcium-binding protein A11, S100A11 and MLN70, is a member of theS-100 family. S100A11 is widely expressed in multiple tissues, and is located in cytoplasm, nucleus, and even cell periphery. S100A11 exists as a non-covalent homodimer with an antiparallel conformation. Ca(2+) binding to S100A11 would trigger conformational changes which would expose the hydrophobic cleft of S100A11 and facilitate its interaction with target proteins. As a dual cell growth med...
TMPY-01926	S100A10 Protein, Human, Recombinant (His) ANX2L,S100 calcium binding protein A10,p10...	Human	E. coli
	S100 protein is a family of low molecular weight protein found in vertebrates characterized by two EF-hand calcium-binding motifs. There are at least 21 different S100 proteins, and the name is derived from the fact that the protein is 100% soluble in ammonium sulfate at neutral pH. Most S100 proteins are disulfide-linked homodimer, and is normally present in cells derived from the neural crest, chondrocytes, macrophages, dendritic cells, etc. S1 proteins have been implicated in a variety of int...
TMPY-03556	S100A8 Protein, Mouse, Recombinant (His) p8,S100 calcium binding protein A8,Caga,60...	Mouse	E. coli
	S100A8 is a member of the S100 protein family containing 2EF-hand calcium-binding motifs. S100 proteins are involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. Altered expression of S100A8 protein is associated with various diseases and cancers. S100A8 may have an immunoregulatory role by contributing to the regulation of fetal-maternal interactions. It may play a protective role and its absence may allow infiltration by maternal cells...
TMPK-01324	S100A9 Protein, Canine, Recombinant (His) MRP-14,CAGB,MRP14,p14,S100-A9,Calprotectin...	Canine	E. coli
	S100A8 and S100A9 (also known as MRP8 and MRP14, respectively) are Ca2 binding proteins belonging to the S100 family. They often exist in the form of heterodimer, while homodimer exists very little because of the stability. S100A8/A9 is constitutively expressed in neutrophils and monocytes as a Ca2 sensor, participating in cytoskeleton rearrangement and arachidonic acid metabolism.
TMPY-03020	S100B Protein, Mouse, Recombinant (hFc) AI850290,S100 calcium binding protein B,Bp...	Mouse	HEK293
	S100B is a member of the S100 family of proteins containing two EF-hand-type calcium-binding motifs. S100B exerts both intracellular and extracellular functions. Intracellular S100B acts as a stimulator of cell proliferation and migration and an inhibitor of apoptosis and differentiation, which might have important implications during brain, cartilage and skeletal muscle development and repair, activation of astrocytes in the course of brain damage and neurodegenerative processes, and of cardiom...
TMPY-02222	S100A3 Protein, Human, Recombinant (His & MBP) S100 calcium binding protein A3,S...	Human	E. coli
	Protein S100-A3, also known as Protein S-100E, S100 calcium-binding protein A3, S100A3 and S100E, is a member of the S-100 family. S100A3 / S100E contains 2 EF-hand domains. S100A3 / S100E is highly expressed in the differentiating cuticular cells within the hair follicle and organized into mature hair cuticles. High concentrations of S100A3 homotetramer might provide the millimolar level of Ca2+required for hair cuticular barrier formation. S100A3 / S100E is a unique member of the Ca2+-binding ...
TMPH-03358	S100A9 Protein, Rat, Recombinant (His & SUMO)	Rat	E. coli
	S100A9 Protein, Rat, Recombinant (His & SUMO) is expressed in E. coli.
TMPH-00297	S100A9 Protein, Bovine, Recombinant (His & Myc & SUMO)	Bovine	E. coli
	S100A9 is a calcium- and zinc-binding protein which plays a prominent role in the regulation of inflammatory processes and immune response. It can induce neutrophil chemotaxis, adhesion, can increase the bactericidal activity of neutrophils by promoting phagocytosis via activation of SYK, PI3K/AKT, and ERK1/2 and can induce degranulation of neutrophils by a MAPK-dependent mechanism. Predominantly found as calprotectin (S100A8/A9) which has a wide plethora of intra- and extracellular functions. T...
TMPK-01412	HLA-B*15:01&B2M&SARS-CoV-2 epitope (NQKLIANQF) Monomer Protein, Human, MHC (His & Avi) SARS-CoV-2 epitope,MHC	Human	HEK293
	HLA-B15:01 is strongly associated with asymptomatic infection with SARS-CoV-2 and is likely to be involved in the mechanism underlying early viral clearance. T cells from pre-pandemic individuals carrying HLA-B15:01 were reactive to the immunodominant SARS-CoV-2 S-derived peptide NQKLIANQF, and 100% of the reactive cells displayed memory phenotype.
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重组蛋白

S100B Protein, Mouse, Recombinant (His)

Cat.No: TMPJ-00990

Species: Mouse

Expression System: E. coli

S100A8 & S100A9 Heterodimer Protein, Human, Recombinant (Flag & His)

Cat.No: TMPY-04290

Species: Human

Expression System: Baculovirus-Insect Cells

S100B Protein, Canine, Recombinant (hFc)

Cat.No: TMPK-01369

Species: Canine

Expression System: HEK293

S100B Protein, Human, Recombinant (His)

Cat.No: TMPY-02531

Species: Human

Expression System: E. coli

S100A1 Protein, Human, Recombinant

Cat.No: TMPY-00997

Species: Human

Expression System: E. coli

S100A1 Protein, Mouse, Recombinant (His)

Cat.No: TMPY-02532

Species: Mouse

Expression System: E. coli

S100A1 Protein, Human, Recombinant (hFc)

Cat.No: TMPY-00909

Species: Human

Expression System: HEK293

S100B Protein, Human, Recombinant (hFc)

Cat.No: TMPY-00913

Species: Human

Expression System: HEK293

S100A9 Protein, Human, Recombinant (His)

Cat.No: TMPY-01357

Species: Human

Expression System: Baculovirus-Insect Cells

S100A8 Protein, Human, Recombinant (His)

Cat.No: TMPY-01356

Species: Human

Expression System: Baculovirus-Insect Cells

S100P Protein, Human, Recombinant

Cat.No: TMPY-02216

Species: Human

Expression System: E. coli

S100A16 Protein, Human, Recombinant

Cat.No: TMPY-02135

Species: Human

Expression System: E. coli

S100A9 Protein, Human, Recombinant

Cat.No: TMPY-01330

Species: Human

Expression System: E. coli

S100A6 Protein, Mouse, Recombinant

Cat.No: TMPY-01094

Species: Mouse

Expression System: E. coli

S100A15A Protein, Mouse, Recombinant

Cat.No: TMPJ-01189

Species: Mouse

Expression System: E. coli

S100A8 Protein, Rat, Recombinant (His)

Cat.No: TMPJ-00991

Species: Rat

Expression System: E. coli

S100A9 Protein, Mouse, Recombinant (His)

Cat.No: TMPY-02821

Species: Mouse

Expression System: E. coli

S100P Protein, Human, Recombinant, Biotinylated

Cat.No: TMPY-04944

Species: Human

Expression System: E. coli

S100A4 Protein, Human, Recombinant (His)

Cat.No: TMPY-03934

Species: Human

Expression System: E. coli

S100P Protein, Human, Recombinant (His)

Cat.No: TMPJ-00917

Species: Human

Expression System: E. coli

Psoriasin/S100A7 Protein, Human, Recombinant

Cat.No: TMPY-01346

Species: Human

Expression System: E. coli

S100A4 Protein, Mouse, Recombinant

Cat.No: TMPY-04080

Species: Mouse

Expression System: HEK293

S100A14 Protein, Human, Recombinant (His)

Cat.No: TMPY-01879

Species: Human

Expression System: E. coli

S100A13 Protein, Mouse, Recombinant (His)

Cat.No: TMPY-03699

Species: Mouse

Expression System: E. coli

S100A3 Protein, Mouse, Recombinant (His)

Cat.No: TMPY-03335

Species: Mouse

Expression System: E. coli

S100A5 Protein, Human, Recombinant (His)

Cat.No: TMPY-01931

Species: Human

Expression System: E. coli

S100A13 Protein, Human, Recombinant

Cat.No: TMPY-01476

Species: Human

Expression System: E. coli

S100A12 Protein, Human, Recombinant

Cat.No: TMPY-01466

Species: Human

Expression System: E. coli

S100A11 Protein, Human, Recombinant

Cat.No: TMPY-01331

Species: Human

Expression System: E. coli

S100A2 Protein, Human, Recombinant

Cat.No: TMPY-00998

Species: Human

Expression System: E. coli

S100A6 Protein, Human, Recombinant

Cat.No: TMPY-00912

Species: Human

Expression System: E. coli

S100A5 Protein, Mouse, Recombinant (His)

Cat.No: TMPY-02463

Species: Mouse

Expression System: E. coli

S100A6 Protein, Human, Recombinant (His)

Cat.No: TMPY-01339

Species: Human

Expression System: Baculovirus-Insect Cells

S100A4 Protein, Human, Recombinant (hFc)

Cat.No: TMPY-00911

Species: Human

Expression System: HEK293

S100A4 Protein, Mouse, Recombinant (His)

Cat.No: TMPY-04111

Species: Mouse

Expression System: E. coli

S100A9 Protein, Cynomolgus, Recombinant (His)

Cat.No: TMPK-01259

Species: Cynomolgus

Expression System: E. coli

S100A15 Protein, Mouse, Recombinant (His & MBP)

Cat.No: TMPY-02497

Species: Mouse

Expression System: E. coli

S100A2 Protein, Human, Recombinant (hFc)

Cat.No: TMPY-00910

Species: Human

Expression System: HEK293

S100A7A Protein, Human, Recombinant (His)

Cat.No: TMPH-01951

Species: Human

Expression System: Yeast

S100A4 Protein, Rat, Recombinant (His & Myc)

Cat.No: TMPH-03357

Species: Rat

Expression System: E. coli

S100A4 Protein, Mouse, Recombinant (hFc)

Cat.No: TMPY-03938

Species: Mouse

Expression System: HEK293

S100A11 Protein, Mouse, Recombinant (His)

Cat.No: TMPY-03700

Species: Mouse

Expression System: E. coli

S100A10 Protein, Human, Recombinant (His)

Cat.No: TMPY-01926

Species: Human

Expression System: E. coli

S100A8 Protein, Mouse, Recombinant (His)

Cat.No: TMPY-03556

Species: Mouse

Expression System: E. coli

S100A9 Protein, Canine, Recombinant (His)

Cat.No: TMPK-01324

Species: Canine

Expression System: E. coli

S100B Protein, Mouse, Recombinant (hFc)

Cat.No: TMPY-03020

Species: Mouse

Expression System: HEK293

S100A3 Protein, Human, Recombinant (His & MBP)

Cat.No: TMPY-02222

Species: Human

Expression System: E. coli

S100A9 Protein, Rat, Recombinant (His & SUMO)

Cat.No: TMPH-03358

Species: Rat

Expression System: E. coli

S100A9 Protein, Bovine, Recombinant (His & Myc & SUMO)

Cat.No: TMPH-00297

Species: Bovine

Expression System: E. coli

HLA-B*15:01&B2M&SARS-CoV-2 epitope (NQKLIANQF) Monomer Protein, Human, MHC (His & Avi)

Cat.No: TMPK-01412

Species: Human

Expression System: HEK293

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